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Palms in the Amazon jungle

Your Complete Guide to Ayahuasca in America

Americans searching for ayahuasca have more legal options today than ever before. This page helps you understand them.

If you're researching ayahuasca retreats in America, you've likely encountered a confusing landscape: conflicting information about legality, underground ceremonies, religious exemptions, and "decriminalized" cities.

Interest in the use of psychedelics is rising. In early 2025 the UC Berkeley Center for the Science of Psychedelics did a study on people's perceptions about the use of psychedelics in society. 55% of respondents reported that they or someone close to them have used psychedelics at some point in their lives, up from 52% in 2023.

This page provides what we wish existed when we started this work: an honest, comprehensive overview of your options for working with ayahuasca legally in the United States, how to evaluate any retreat center, and why some Americans ultimately choose Peru.

We run an ayahuasca retreat center in Peru and have hosted Americans since 2010. We're not going to pretend domestic options don't exist. They do. We'll tell you about them honestly, then explain why the traditional setting still matters to many people.


Is Ayahuasca Legal in the USA?

The short answer: federally illegal, with narrow religious exemptions.

Federal Law

DMT—the primary psychoactive compound in ayahuasca—is classified as a Schedule I substance under the Controlled Substances Act. Possession, manufacture, and distribution are federal crimes.

However, the Religious Freedom Restoration Act (RFRA) of 1993 provides a pathway for religious organizations to petition the DEA for exemption. Several churches have successfully obtained legal protection through court victories or DEA approval.

State Decriminalization

In November 2022, Colorado passed the Natural Medicine Health Act, decriminalizing personal possession and use of DMT-containing plants for adults 21+. Several cities (Oakland, Santa Cruz, Seattle, Detroit, and others) have passed similar "lowest law enforcement priority" resolutions.

Important: Decriminalization is not legalization. It removes state/local criminal penalties for personal use, but:

  • Federal law still applies
  • Commercial sale and distribution remain illegal
  • No regulatory framework exists for retreat centers
  • You have no consumer protections or safety standards

Colorado plans to include DMT in its regulated access framework as early as 2026, which could create the first legal commercial pathway. For now, decriminalization protects individuals, not businesses.

The "Municipal Illusion"

Be cautious of retreat centers claiming they're "legal" because they operate in a decriminalized city. These resolutions make enforcement a low priority for local police—they don't provide immunity from federal prosecution, don't regulate safety, and don't protect you if something goes wrong.


Legally-Protected Ayahuasca Churches in the USA

As of January 2026, four religious organizations have confirmed federal legal protection to use ayahuasca in ceremonies. These are legitimate options worth understanding.

UDV (União do Vegetal)

Legal status: Supreme Court victory, 2006 (Gonzales v. UDV)

The Centro Espírita Beneficente União do Vegetal is a Brazilian Christian Spiritist religion with approximately 600 members in the United States. In 2006, the U.S. Supreme Court unanimously affirmed their right to use ayahuasca (which they call "Hoasca") in religious ceremonies.

  • Locations: Colorado, New Mexico, California, Connecticut, Florida, Texas, Washington
  • Structure: Religious community with membership process—not open public retreats
  • What to expect: Commitment to the religious practice, not drop-in ceremonies

UDV is a genuine religious community, not a therapeutic retreat center. If you're seeking a spiritual path rather than a one-time experience, this may be appropriate.

Santo Daime Churches

Legal status: Federal court injunction, 2009 (Church of the Holy Light of the Queen v. Mukasey)

Santo Daime is a syncretic religion combining Christian, indigenous, and African spiritual elements. Several U.S. branches have explicit legal permission to use ayahuasca (called "Daime") in ceremonies.

  • Church of the Holy Light of the Queen — Ashland, Oregon (since 1996)
  • Church of the Divine Rose — Portland, Oregon
  • Flower of the Divine Mother — Southern California
  • Additional branches in Massachusetts and Washington State

Santo Daime ceremonies are religious services with specific hymns, rituals, and community expectations. They're not structured as therapeutic retreats but as ongoing spiritual practice.

Church of the Eagle and the Condor

Legal status: DEA settlement, April 2024

A Phoenix-based church inspired by Shipibo-Conibo traditions of Peru. After the government seized their ayahuasca shipment in 2020, they filed suit and reached a settlement allowing them to legally import and use ayahuasca.

  • Location: Phoenix, Arizona
  • Significance: First non-Christian church to receive ayahuasca protection
  • Traditions: Shipibo-Conibo ceremonial practices

This is a small, relatively new church. Contact them directly to understand their membership process and ceremony schedule.

Church of Gaia

Legal status: DEA approval, May 2025

The Church of Gaia in Spokane, Washington became the first organization to receive DEA approval for ayahuasca use without filing a lawsuit—a significant legal milestone.

  • Location: Spokane, Washington (ceremonies on rural property)
  • Size: Approximately 50 members; ceremonies limited to 10 participants
  • Traditions: Shipibo-Conibo ceremonial leaders from Peru
  • Process: Membership requires screening interview and preliminary paperwork

Church of Gaia is very new to legal operation (ceremonies began late 2025). As the first church approved through the non-litigation pathway, their model may influence future applications.

Note on legally-protected churches: These organizations have genuine legal protection, but they are religious communities, not therapeutic retreat centers. Most require membership, ongoing participation, and alignment with their spiritual framework. If you're seeking a single transformative experience rather than a religious path, these may not be the right fit.

Other Ayahuasca Centers Operating in the USA

Beyond the four legally-protected churches, numerous centers operate across the United States claiming various forms of religious or legal protection. We're listing the most established ones here so you can research them yourself.

Pachamama Sanctuary (Maine)

The largest ayahuasca center in the United States, founded in 2019 and relocated from New Hampshire to Casco, Maine. They hold a 4.92/5 rating from over 200 reviews on Retreat Guru.

  • Format: Weekend retreats with two ceremonies, breathwork, integration circles
  • Cost: ~$888 (suggested donation)
  • Legal basis: Claims religious exemption (not formally DEA-approved)

Kamentsa Inga Church (New Hampshire)

Led by Taita Hector Ortiz from Colombia, offering ceremonies in New Hampshire and other states. Holds a 5-star rating from reviews on AyaAdvisors.

  • Traditions: Colombian Kamentsa indigenous practices
  • Cost: ~$250 for 1-2 day retreats
  • Legal status: Ongoing federal lawsuit seeking formal protection (Kamentsa Inga Church v. Garland, 2023)

OME Retreats / OM Divinity Church

OME Retreats operates in multiple states (Georgia, Texas, California, Florida) with Peruvian-initiated facilitators working in Shipibo traditions.

  • Format: Weekend ceremonies
  • Legal basis: Claims religious protection
  • Note: Fewer independent reviews available compared to other centers

Ágape Church (Texas)

A Texas-based church offering ayahuasca ceremonies with claimed religious exemption.

  • Location: Central Texas
  • Cost: ~$1,250
Important: Centers operating without formal DEA approval are in legal grey areas. This doesn't mean they're unsafe or illegitimate—many are run by sincere people with genuine healing intent. But it does mean you have less legal recourse if something goes wrong, and the center's continued operation is not guaranteed.

How to Research Any Ayahuasca Retreat

Whether you're considering a US-based center or traveling abroad, thorough research is essential. The ayahuasca space has no regulatory oversight in most places—you are your own quality control.

Red Flags to Watch For

  • No medical screening: Any responsible center requires detailed health questionnaires and reviews your medications. Ayahuasca has dangerous interactions with SSRIs, MAOIs, blood pressure medications, and other drugs. If a center doesn't ask about your health, walk away.
  • Instant booking without conversation: Legitimate facilitators want to speak with you before ceremony. If you can book online without any human contact, that's concerning.
  • Guaranteed results or "miraculous cures": No one can promise specific outcomes. Be wary of marketing that sounds too good to be true.
  • Unclear facilitator credentials: Where did they train? How long? With whom? Vague answers or refusal to discuss lineage is a warning sign.
  • Very large group sizes: Traditional ceremonies typically involve 10-20 people maximum. Centers running 50+ person ceremonies cannot provide adequate individual attention. It is unlikely the energy of the ceremonial space can be adequately managed with large number of people participating.
  • Pushy sales tactics or pressure: Authentic healers don't use high-pressure marketing.
  • No integration support: The ceremony is just the beginning. Centers with no follow-up, no sharing circles, and no integration guidance are missing a critical component.

Questions to Ask Before Booking

  • What is your medical screening process?
  • What are your emergency protocols if someone has a medical or psychological crisis?
  • Who leads ceremonies? What is their training and experience?
  • How many ceremonies have they facilitated?
  • What is the maximum group size?
  • What integration support do you offer before and after?
  • What is your legal basis for operating? (If in the US)
  • Can I speak with past participants?

Trustworthy centers will answer these questions directly and thoroughly. Evasion or defensiveness is itself a red flag.

Where to Find Independent Reviews

Don't rely solely on testimonials from a center's own website. Cross-reference with independent sources:

  • AyaAdvisors — Over 5,000 ayahuasca retreat reviews from verified participants
  • BestRetreats.co — Tracks incident history, Reddit discussions, and red flags
  • SafeCeremonies.com — Safety-focused retreat verification
  • Reddit communities — r/Ayahuasca, r/Psychedelics — search for the specific center name
  • Google reviews and TripAdvisor — Look for patterns in negative reviews especially

Pay attention to patterns across multiple reviews, not individual experiences. One negative review could be an outlier; five people reporting similar problems is a signal.

Recent Incidents Worth Knowing About

Transparency matters. Here are documented incidents that illustrate why due diligence is critical:

  • Soul Quest (Florida): In 2018, a 22-year-old participant died from hyponatremia after ceremonies. In May 2024, a jury ordered the center and its owner to pay $15 million in wrongful death damages. The center filed for bankruptcy and closed in August 2024.
  • Ayahuasca Healings: This center claimed to be "the first legal ayahuasca church in America" in 2015-2016. Experts including MAPS founder Rick Doblin called these claims false. The center is now defunct.

These cases highlight the importance of verifying legal claims and checking safety track records. Centers with genuine legal protection and strong safety cultures exist—but so do those cutting corners.


Why Some Americans Choose Peru

Given that legal options exist in the United States, why do many Americans still travel to Peru for ayahuasca? We've hosted hundreds of American guests since 2010. Here's what they tell us.

Complete Legal Clarity

In Peru, ayahuasca is recognized as national cultural heritage. There's no legal grey area, no pending litigation, no risk of a center closing mid-planning. You can surrender fully to the experience without anxiety about legal status.

Lineage-Based Healers

The Mestizo healing traditions around Iquitos involve years of apprenticeship: extended plant dietas (strict isolation and fasting with specific teacher plants), gradual transmission of icaros (healing songs), and supervised practice passed through family lineages.

At Hummingbird Healing Centre, Maestro Manain is a fourth-generation Mestizo ayahuascero from the Iquitos area with over 45 years of experience. This isn't a credential that can be obtained in a weekend workshop.

Depth of Container

Most US-based ceremonies are single nights or weekends. You arrive, drink, and return to your life Monday morning—often while still processing difficult material.

Our retreats are structured differently:

  • 9 to 28 days of continuous immersion
  • Multiple ceremonies allowing deeper layers to emerge
  • Daily integration circles to process what arises
  • Complementary practices: Huachuma (San Pedro) ceremonies, plant baths, meditation
  • Medical screening before arrival
  • Conservative initial dosing based on your experience

The Medicine in Its Home Context

There's something different about drinking ayahuasca in the Amazon rainforest—surrounded by the sounds, scents, and energy of the jungle where this tradition evolved over millennia. The setting itself becomes part of the healing.

Many American guests tell us the physical distance from their daily lives helped them access deeper work. You can't check your inbox between ceremonies. Your familiar patterns and coping mechanisms don't travel well across hemispheres.

Cost Comparison

US-based retreats often cost $1,000-$3,500 for a weekend. A 9-day immersive retreat at Hummingbird—including accommodation, all meals, multiple ceremonies, integration support, and complementary practices—may cost less than a single weekend domestically, even factoring in airfare.


USA-Specific Considerations

Medications and Healthcare

If you take prescription medications—especially psychiatric medications—careful planning is essential before any ayahuasca experience, whether in the US or abroad.

Medications contraindicated with ayahuasca include:

  • SSRIs (e.g., Lexapro, Zoloft, Prozac)
  • SNRIs (e.g., Effexor, Cymbalta)
  • MAOIs
  • Some blood pressure medications
  • Tramadol and certain other pain medications
  • Some antihistamines

These combinations can cause serotonin syndrome, which can be fatal. Some medications require supervised tapering over weeks or months. We conduct thorough medical screening and will discuss any concerns before you book.

Important: This page provides information, not medical advice. Discuss any planned retreat participation with your prescribing physician.

Travel to Peru

Good news: US passport holders do not need a tourist visa for Peru.

  • You'll receive a stamp on arrival
  • Stays up to 90 days permitted
  • Passport must be valid for at least six months from entry date

Getting there:

  1. US to Lima — Direct flights available from Miami, Houston, Atlanta, Los Angeles, New York (5-8 hours depending on origin)
  2. Lima to Iquitos — Domestic flight, approximately 2 hours. Several daily flights.
  3. Iquitos to centre — We arrange ground transport to Hummingbird Healing Centre.

For detailed routing, packing lists, and arrival guidance, see: Travelling to Iquitos

Integration Support Back Home

Integration—translating ceremony insights into lasting change—is where transformation becomes sustainable. Before you travel, consider lining up:

  • A therapist or counselor open to discussing non-ordinary states of consciousness
  • An integration coach with plant medicine experience
  • Community support—friends, family, or groups who understand this work

Organizations like MAPS Integration List and the Fluence Directory can help you find psychedelic-informed therapists in your area.


Hummingbird Healing Centre: Trusted by Americans Since 2010

We've hosted guests from across the United States—New York, California, Texas, Florida, and everywhere in between. We understand the decision to travel internationally for this work, and we take that trust seriously.

Master Shaman & Facilitators

Maestro Manain is a 4th-generation Mestizo ayahuascero with 45+ years of experience. Jim Davis has guided 1,400+ ceremonies since 2010. Meet Our Team

Multiple Retreat Lengths

9-day, 12-day, and 3-4 week immersion options allow for depth that weekend ceremonies cannot provide. View Retreats

Safety Protocols

Comprehensive medical screening, conservative dosing, attentive monitoring. 15+ years without a medical emergency related to ayahuasca. Ayahuasca Safety

Integration Focus

Daily sharing circles, educational talks, connections to integration specialists. About Integration

Huachuma (San Pedro) Included

All retreats include at least one Huachuma ceremony—a heart-opening complement to ayahuasca's work. Huachuma Healing

Private Accommodation

Private tambos (jungle huts) with bed, toilet, hammock, and writing desk. Accommodation

Natural Setting

Located 14km outside Iquitos in quiet jungle—complete separation from daily life. Centre Location

Extra Healing Activities

Plant baths, guided jungle walks, meditation, breathwork, talks on integration and transformation.


[Testimonials from American guests will be added here]


Next Steps

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